Cytisinicline is a natural, plant-based investigational drug that is being evaluated in the United States as an aid to smoking cessation.  The ORCA-3 study is a randomized, placebo-controlled Phase 3 clinical trial currently being conducted to assess the effectiveness and safety of cytisinicline.

ORCA-3 is now fully enrolled with more than 750 adults from the following cities who currently smoke cigarettes daily and intend to quit smoking.

Clinical Trial Locations: